Statin therapy for acute respiratory distress syndrome: an individual patient data meta-analysis of randomised clinical trials.
Identifieur interne : 000351 ( Main/Exploration ); précédent : 000350; suivant : 000352Statin therapy for acute respiratory distress syndrome: an individual patient data meta-analysis of randomised clinical trials.
Auteurs : Myura Nagendran [Royaume-Uni] ; Daniel F. Mcauley [Royaume-Uni] ; Peter S. Kruger [Australie] ; Laurent Papazian [France] ; Jonathon D. Truwit [États-Unis] ; John G. Laffey [Canada] ; B Taylor Thompson [États-Unis] ; Mike Clarke [Royaume-Uni] ; Anthony C. Gordon [Royaume-Uni]Source :
- Intensive care medicine [ 1432-1238 ] ; 2017.
Descripteurs français
- KwdFr :
- Adulte, Analyse de régression, Creatine kinase (sang), Essais contrôlés randomisés comme sujet, Femelle, Humains, Inhibiteurs de l'hydroxyméthylglutaryl-CoA réductase (usage thérapeutique), Mâle, Résultat thérapeutique, Syndrome de détresse respiratoire de l'adulte (enzymologie), Syndrome de détresse respiratoire de l'adulte (mortalité), Syndrome de détresse respiratoire de l'adulte (traitement médicamenteux), Transaminases (sang).
- MESH :
- enzymologie : Syndrome de détresse respiratoire de l'adulte.
- mortalité : Syndrome de détresse respiratoire de l'adulte.
- sang : Creatine kinase, Transaminases.
- traitement médicamenteux : Syndrome de détresse respiratoire de l'adulte.
- usage thérapeutique : Inhibiteurs de l'hydroxyméthylglutaryl-CoA réductase.
- Adulte, Analyse de régression, Essais contrôlés randomisés comme sujet, Femelle, Humains, Mâle, Résultat thérapeutique.
English descriptors
- KwdEn :
- Adult, Creatine Kinase (blood), Female, Humans, Hydroxymethylglutaryl-CoA Reductase Inhibitors (therapeutic use), Male, Randomized Controlled Trials as Topic, Regression Analysis, Respiratory Distress Syndrome, Adult (drug therapy), Respiratory Distress Syndrome, Adult (enzymology), Respiratory Distress Syndrome, Adult (mortality), Transaminases (blood), Treatment Outcome.
- MESH :
- chemical , blood : Creatine Kinase, Transaminases.
- chemical , therapeutic use : Hydroxymethylglutaryl-CoA Reductase Inhibitors.
- drug therapy : Respiratory Distress Syndrome, Adult.
- enzymology : Respiratory Distress Syndrome, Adult.
- mortality : Respiratory Distress Syndrome, Adult.
- Adult, Female, Humans, Male, Randomized Controlled Trials as Topic, Regression Analysis, Treatment Outcome.
Abstract
We performed an individual patient data meta-analysis to assess the possible benefits and harms of statin therapy in adults with acute respiratory distress syndrome (ARDS) and to investigate effects in specific ARDS subgroups.
DOI: 10.1007/s00134-016-4649-0
PubMed: 28004129
Affiliations:
- Australie, Canada, France, Royaume-Uni, États-Unis
- Massachusetts, Ontario, Provence-Alpes-Côte d'Azur, Wisconsin
- Marseille, Toronto
- Université de Toronto
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Le document en format XML
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<term>Creatine Kinase (blood)</term>
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<term>Hydroxymethylglutaryl-CoA Reductase Inhibitors (therapeutic use)</term>
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<term>Respiratory Distress Syndrome, Adult (drug therapy)</term>
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<front><div type="abstract" xml:lang="en">We performed an individual patient data meta-analysis to assess the possible benefits and harms of statin therapy in adults with acute respiratory distress syndrome (ARDS) and to investigate effects in specific ARDS subgroups.</div>
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